| Cell type (class) | Nomenclature (Acronym) |
Definition | Relation of LHA-projecting retinal ganglion cell |
| Annotation | Reference |
Collator |
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| glutamate/PACAP expressing retinal ganglion cell | Hannibal et al. (Hannibal) | In the retina PACAP immunoreactivity was located to a homogeneous population of retinal ganglion cells with two to four thin, sparsely branching processes (Fig. 2A). Most processes seemed to radiatel horizontally in the ganglion cell layer towards the optic disc via the optic nerve. Other processes projected through the inner plexiform layer towards the inner nuclear layer in which they seemed to may synaptic contact (Fig. 3A). | partial correspondence | | ...a relatively dense accumulation of ChB-containing retinal projections with a marked contralateral dominance was located in the....LH dorsal to the supraoptic nucleus. ... only a small fraction of the ChB immunoreactive fibres in the LH contained PACAP (Fig.1J-L). | Hannibal J. & Fahrenkrug J. | Mihail Bota |
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| retinal ganglion cell type III | Perry (Perry) | Type III cells have small bodies but they have the largest range of dendritic field sizes (see table 1). The dendrites of this cell class branch less frequently than those of the other classes. This group of cells encompasses a slightly wider variety of dendritic morphology, than the other three classes. | is included | | The size and morphology of these cells are consistent with the type III classification of Perry [24]. | Leak R.H. & Moore R.Y. | Mihail Bota |
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| SCN-projecting retinal ganglion cell | Moore (Moore) | Examination of whole mounts of a retina contralateral to the injected eye reveals a population of infected ganglion cells that appears to have a relatively uniform distribution across the retina. Individual neurosn have spherical-to-oval perikarya with two-to-four thin, sparsely branching proximal dendrites (Fig. 5). Dendrites extend radially from the cell soma, but the full extent of the dendritic arbors cannot be determined because the viral immunoreactivity does not extend into distal dendrites.... With Flurogold injections into the SCN that do not appear to extend into the optic chiasm, the labeled ganglion cells have a median area of 100 micrometers square. The mean area is 109.7 micrometers square and the mean diameter is 14.3 micrometers square. In addition ot the large numbers of small ganglion cells labeled there is a small number of larger cells with areas ranging from 160 to 250 micrometers square and diameters ranging from 18 to 22 micrometers. The data for the PRV injections in intact animals appear similar except that the median area (70 micrometers square), mediam diameter (12 micrometers), mean area (96.2 micrometers square) and mean diameter (13.7 micrometers) are all smaller than in the Fluorogold group. ...We interpret these differences to reflect that both the Fluorogold group and the intact PRV group are showing labeled ganglion cells that project to areas other than the SCN. | different | | Injections of FluoroGold restricted to the LHA label a small population of cells located almost exclusively in the superior temporal retina. This is in contrast with the retinal ganglion cells projecting to the SCN, which are distributed across the whole retina with a slighter higher density in temporal quadrants [22]. Both have a fairly similar mean diameter and area as sparse, fine primary dendrites, as one would expect for type III cells [22]. However, the unique distribution of LHA afferent cells suggests that they may comprise a group separate from the ganglion cells projecting to the SCN. This is supported by studies using the transynaptic tracer pseudorabies virus, Bartha strain [1, 22]. Following injections of PRV Bartha into one eye, the virus is taken up by retinal ganglion cells and trasnported anterogradely to the hypothalamus. There it is released and taken up and replicated by cells in the SCN and adjacent medial hypothalamic areas. However, neurons in the LHA are not infected until late timepoints. | Leak R.H. & Moore R.Y. | Mihail Bota |
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