| Cell type (class) | Nomenclature (Acronym) |
Definition | Relation of superficial spiny neuron |
| Annotation | Reference |
Collator |
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| BNSTALG Type I neuron | Hammack et al. (Hammack) | Type I neurons accounted for 29% of all recorded BNSTALG neurons, had a resting membrane potential (Vm) of -60.0 ± 0.6 mV, and a mean input resistance (Rm) of 452.6 ± 30.0 MOhms. In response to transient (750-ms) hyperpolarizing current injection, Type I neurons exhibited a characteristic depolarizing sag (rectification) in their voltage response that was both time dependent and voltage dependent, such that the amplitude and rate of onset of the rectification increased with increasing membrane hyperpolarization (see Fig. 2B, Type I). Type I neurons also exhibited a transient depolarizing rebound potential on termination of the hyperpolarizing current injection, the amplitude and rate of onset of which also increased with increasing levels of initial membrane hyperpolarization. | partial correspondence | | Collator note: this relation is inferred by the collator on the basis of morphology of both neurons populations (soma size, shape and pattern of dendritic arborizations), and location in the same nucleus. The superficial spiny neurons may be one the of several classes that express 5HTA1 receptors in BST. See Larriva-Sahd, 2006 for a detailed cytological description. | Marvin E., Scrogin K. & Dudas B. | Mihail Bota |
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| BNSTALG Type II neuron | Hammack et al. (Hammack) | Type II neurons were the most abundant of BNSTALG neurons, accounting for 55% of all recorded cells. These neurons had a Vm of -58.0 &plusm; 0.5 mV and an Rm of 377.4 & 15.7 MOhms.. Type II neurons also exhibited a depolarizing sag in response to hyperpolarizing current injection that was similar to that described for Type I neurons. However, in contrast to Type I neurons, the amplitude and rate of onset of the rebound depolarization observed at the termination of the hyperpolarizing current
injection were always much larger than the degree of depolarizing rectification observed. Significantly, the amplitude of the rebound depolarization often surpassed action potential threshold and triggered a rebound burst of action potentials (see Fig. 2B, Type II), suggesting that Type II neurons express additional active currents that could be modulated by prior membrane hyperpolarization. After the initial burst of action potentials, Type II neurons either fire in a regular pattern (Fig. 2A, Type II), fire in bursts, or stop firing altogether (accommodate). The variability of this second response is likely explained by the differential expression of outward rectifying currents and calcium-dependent potassium currents, and/or differences in the properties of the calcium currents that generate the initial burst. These differences suggest that even within Type II neurons there is heterogeneity in their physiological responses. | partially corresponds | | Collator note: Type II neurons appear to be distributed over several anterior BST regions. We chose "overlap" relationship, because no systematic study was made to unequivocally map this neuron-type over the possible morphological types. See also Larriva-Sahd, 2006 | Hammack S.E., Mania E. & Rainnie D.G. | Mihail Bota |
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