BAMS | Inferred network

Inferred network

R(Retina) → PVH(Paraventricular nucleus of the hypothalamus)
PVH(Paraventricular nucleus of the hypothalamus) → PAG(Periaqueductal gray)
PAG(Periaqueductal gray) → VTA(Ventral tegmental area)
VTA(Ventral tegmental area) → LHA(Lateral hypothalamic area)

Support information about direct projections from Retina to Paraventricular nucleus of the hypothalamus:

Sending structure	Receiving structure	Strength of projection	Type of connection	Technique	General description	Collator	Associated reference
Retina	Paraventricular nucleus of the hypothalamus	moderate	not known	Cholera toxin conjugated to HRP	Case pg348, fig2. Soma notes 36 female Sprague-Dawley rats weighing 200-350g. 10 microliters of CT-HRP(.20%-.40%) were injected into one eye ?behind the lens into the vitreous chamber of the eye. pressure injection over 1 min. Terminal notes Medial component of the RHT: a few fibres were seen in the PVN in some rats but this label was not consistently evident.		Levine JD, Weiss ML, Rosenwasser AM, Miselis RR., 1991

Support information about direct projections from Paraventricular nucleus of the hypothalamus to Periaqueductal gray:

Sending structure	Receiving structure	Strength of projection	Type of connection	Technique	General description	Collator	Associated reference
Paraventricular nucleus of the hypothalamus	Periaqueductal gray	light	not known	HRP	Case table2. Soma notes not specified.. Terminal notes HRP inj.		Beitz AJ., 1982

Support information about direct projections from Periaqueductal gray to Ventral tegmental area:

Sending structure	Receiving structure	Strength of projection	Type of connection	Technique	General description	Collator	Associated reference
Periaqueductal gray	Ventral tegmental area	light	not known	HRP	Case pg149, R50(no fig), table3. Soma notes smaller numbers of cells. Terminal notes HRP inj into vemtrolateral division (only one inj produced labelling).		Beitz AJ., 1982
Periaqueductal gray	Ventral tegmental area	moderate	not known	HRP	Case pg109, table1, fig1. Soma notes In addition moderate bilateral label is observed in the VTRZ, the nucleus parabrachialis pigmentosus and paranigralis and the compact part of the substantia nigra. Terminal notes The supraoculomotor portion of the periaqueductal gray, has been injected (HRP) in 3 rabbits & 1 rat. In all 4 cases the supraocmot/PAG has been successfully injected with minimal spread to the adjacent occulomotor nucleus..		Giolli RA, Blanks RH, Torigoe Y, Williams DD., 1985

Support information about direct projections from Ventral tegmental area to Lateral hypothalamic area:

Sending structure	Receiving structure	Strength of projection	Type of connection	Technique	General description	Associated reference
Ventral tegmental area	Lateral hypothalamic area	light	not known	autoradiography	Case pg198, fig3. Soma notes 3H proline/3H leucine inj. Terminal notes uncertain whether any AVT fibres actually terminated in the lateral hypothalamic region.	Beckstead RM, Domesick VB, Nauta WJ., 1979
Ventral tegmental area	Lateral hypothalamic area	moderate	not known	fluorescent tracers	Case pg369-71. Soma notes high numbers of neurons. Terminal notes FB inj.	Faye-Lund H., 1985
Ventral tegmental area	Lateral hypothalamic area	moderate	not known	Cholera toxin conjugated to HRP	Case pg615, fig6. Soma notes not specified.. Terminal notes CT inj into VTA, with minor inclusion of medial SN.	Groenewegen HJ, Berendse HW., 1990