Inferred network

R(Retina) → MPO(Medial preoptic area)
MPO(Medial preoptic area) → PRC(Precommissural nucleus)
PRC(Precommissural nucleus) → LPO(Lateral preoptic area)
LPO(Lateral preoptic area) → LHA(Lateral hypothalamic area)

Support information about direct projections from Retina to Medial preoptic area:
Sending structure Receiving structureStrength of projection Type of connectionTechniqueGeneral descriptionCollatorAssociated reference
RetinaMedial preoptic area light/moderatenot knownCholera toxin conjugated to HRP
Case pg348,349, fig5d-f. Soma notes 36 female Sprague-Dawley rats weighing 200-350g. 10 microliters of CT-HRP(.20%-.40%) were injected into one eye ?behind the lens into the vitreous chamber of the eye. pressure injection over 1 min. Terminal notes Medial component of the RHT included labeled fibres and terminals found near the midline involved the medial half of the medial preoptic area?terminals evident in the anterior medial preoptic area Paper describes a.m.p.a. as separate region .
Levine JD, Weiss ML, Rosenwasser AM, Miselis RR., 1991
RetinaMedial preoptic area existsnot knownCholera toxin conjugated to HRP
Case pg351,352, fig5a-f. Soma notes 36 female Sprague-Dawley rats weighing 200-350g. 10 microliters of CT-HRP(.20%-.40%) were injected into one eye ?behind the lens into the vitreous chamber of the eye. pressure injection over 1 min. Terminal notes in preoptic region ros. to SCN. lat. component of RHT labeled terminals and fibres within or lateral to the lateral haf of the medial preoptic area. Terminal label evident in ven. 1/2 of the lateral part of the medial preoptic area.
Levine JD, Weiss ML, Rosenwasser AM, Miselis RR., 1991

Support information about direct projections from Medial preoptic area to Precommissural nucleus:
Sending structure Receiving structureStrength of projection Type of connectionTechniqueGeneral descriptionCollatorAssociated reference
Medial preoptic areaPrecommissural nucleus light/moderatenot knownCTB
In the preoptic regions, relatively sparse numbers of marked cells were observed in the median preoptic, anteroventral periventricular, medial preoptic, anterodorsal preoptic, anteroventral preoptic, and parastrial nuclei, as well as in the undifferentiated part of the medial preoptic area. In addition, a very few retrogradely labeled neurons were noted in the lateral preoptic area (Fig. 3C-F).
Canteras N.S & Goto M., 1999

Support information about direct projections from Precommissural nucleus to Lateral preoptic area:
Sending structure Receiving structureStrength of projection Type of connectionTechniqueGeneral descriptionCollatorAssociated reference
Precommissural nucleusLateral preoptic area strongnot knownPHAL
Proceeding rostrally, large numbers of fibers from the PRC reach the preoptic region, where they appear to provide a dense input to the lateral preoptic area in addition to a sparse input to the anteroventral preoptic nucleus (Fig. 5B,C).
Canteras N.S & Goto M., 1999

Support information about direct projections from Lateral preoptic area to Lateral hypothalamic area:
Sending structure Receiving structureStrength of projection Type of connectionTechniqueGeneral descriptionCollatorAssociated reference
Lateral preoptic areaLateral hypothalamic area lightnot knownHRP/WGA
Case pg427, fig5. Soma notes not specified.. Terminal notes WGA-HRP inj into depressor sites, core of inj site in LHAp/LHAt/VTA/SN.
Allen GV, Cechetto DF., 1993
Lateral preoptic areaLateral hypothalamic area existsnot knownautoradiography
earlier: Nauta Brain 81:319, 1958; cat, Nauta method
Swanson L.W., 1976